I use an nVidia 770, they're slightly faster than the older 680's and about the same price (if not a tad cheaper).
My rig is actually a Hackintosh, but my understanding is that the latest version of Mountain Lion has built-in drivers for the 770, so as long as you don't mind not having a startup screen, it should work fine on a Mac Pro (assuming you have the necessary power connectors).
I also get a close to real time frame rate, usually starts around 22fps and picks up to a solid 24fps halfway through the clip.