Short answer:
reply #999 addresses exactly this issue. Both iso_regs and crop_rec need to adjust the same set of registers (ADTG and CMOS), but the current backend only allows one piece of code to work at a time. In the same group of conflicting items, you will find adtg_gui and the plain old FPS override.
Currently, the above is just a proposed specification, nothing more. I do not have any working code, not even on my PC.
It would probably take me about one week of full-time work to implement it, or maybe 1-2 months it I were to work on it for one day (8 hours) per week. I'm unable to make any meaningful progress
on this particular topic in say 30-minute or even 1 hour slices, as it requires highly skilled and focused work. Back in 2014, while I was actively researching this topic, I was probably spending more than 8 hours per day on ML on average, as I had a very relaxed schedule at job, and very little else to do at home. Now, with a nearly full-time job + family, even one day per week fully dedicated to hobbies would already disrupt my schedule. Just in case anyone is wondering why the progress slowed down so much lately.
So, unless (until?) I'll manage to get my time back, all I can say is... good luck figuring it out!
controversial reduced gain/low-noise-shadows debate/saga
FYI, I don't see this topic controversial at all; I only want to make sure these improvements are real and
measurable. Other things were controversial to me in the past - such as mislabeling ISO 1500 to ISO 100 and claiming massive shadow improvements from that. Of course, ISO 1600 is going to be much cleaner in shadows, compared to ISO 100, all other variables being equal, and ISO 1500 is not going to be much different

Of course, this requires a reasonably solid method for evaluating a sensor response, including measurements of the actual ISO, besides noise levels, and I'm no expert here. I tried to come up with a theory, apparently working reasonably well; the procedure still needs to be automated, the repeatability needs to be evaluated, and one important missing bit is the estimation of sensor response curve, i.e. how linear it actually is. Long answer in previous posts, such as
this one.